IGEMS: the consortium on Interplay of Genes and Environment across Multiple Studies.
نویسندگان
چکیده
The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25-102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.
منابع مشابه
Gene-environment interplay in depressive symptoms: moderation by age, sex, and physical illness.
BACKGROUND Numerous factors influence late-life depressive symptoms in adults, many not thoroughly characterized. We addressed whether genetic and environmental influences on depressive symptoms differed by age, sex, and physical illness. METHOD The analysis sample included 24 436 twins aged 40-90 years drawn from the Interplay of Genes and Environment across Multiple Studies (IGEMS) Consorti...
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عنوان ژورنال:
- Twin research and human genetics : the official journal of the International Society for Twin Studies
دوره 16 1 شماره
صفحات -
تاریخ انتشار 2013